Christina Applegate has shared a deeply personal update on her health, revealing that her long-running battle with multiple sclerosis has progressed to the point where she spends most of her days confined to her bed. The 54-year-old actress, who first disclosed her MS diagnosis in 2021, spoke candidly about the profound toll the autoimmune disease has taken on her mobility and daily life.
Applegate told People magazine that even simple movements can trigger intense pain, making ordinary tasks difficult. Despite these challenges, she continues to prioritize time with her family, particularly her 15-year-old daughter, Sadie. She described the daily ritual of driving her daughter to school as cherished alone time that gives her strength amid her struggles.
The realities of living with MS, including its physical and emotional impacts, are central themes in Applegate’s forthcoming memoir, You With the Sad Eyes, set for release in early March. In the book, she reflects on her career, her tumultuous upbringing, her survival of breast cancer, and the ongoing challenges of chronic illness.
In addition to her memoir, Applegate remains active in the MS community through her podcast MeSsy, co-hosted with friend and fellow MS advocate Jamie-Lynn Sigler, and plans to launch an online platform to connect and support others affected by the condition.
Applegate’s openness about her health journey is part of a broader effort to shed light on the realities of life with multiple sclerosis, emphasizing honesty and connection rather than sugar-coating her experience.