US initiates requirement of Negative Coronavirus Test from UK Travelers

Anyone flying into the United States from the United Kingdom will have to test negative for COVID-19 within 72 hours before their flight, the Centers for Disease Control and Prevention announced last Thursday. The agency cited concerns over a new variant of the coronavirus as the reason for the rule, which goes into effect Monday.

The coronavirus, like all viruses, has regularly mutated as it has spread through the population. Most mutations don’t make a virus behave any differently, but this new variant, which emerged in the UK, does appear to spread more easily than other forms of the virus. However, it does not appear to make people sicker and does not seem to be more deadly, although researchers are still studying that question. Experts say the already authorized COVID-19 vaccines will likely still be effective against it.

The new variant is spreading quickly through London and southeast England. Prime Minister Boris Johnson put the area under stricter lockdown to contain it, and dozens of countries have banned travelers from the UK.  Two US states, New York and Washington, already have UK travel restrictions in place. British Airways, Delta Air Lines and Virgin Atlantic agreed to New York Governor Andrew Cuomo’s request to test travelers flying into the state. Washington is asking people traveling from the UK to quarantine for 14 days.

Anthony Fauci said on Good Morning America that he wouldn’t recommend a full ban on travel from the UK, which he called “draconian.” Testing was a more realistic step, said Fauci, the director of the National Institute of Allergy and Infectious Diseases. The reasoning is this: asking travelers to get COVID-19 tests is a more effective screen than temperature and symptom checks, which don’t end up catching many sick people. Still, a test within three days of traveling won’t be a perfect net: someone could test negative a day before their trip and develop symptoms when they land.

It’s possible that the new variant is already circulating in the US, Fauci said. “When you have this amount of spread within a place like the UK, you really need to assume that it’s here already.”  But there is some very good news coming out of all of it.  It appears that ALL of the versions of the SARS-CoV-2 virus identified to date are neutralized by the current COVID-19 vaccines.

The primary way that these vaccines act is by preventing the spike protein on the exterior of the coronavirus from attaching to the ACE2 protein on human cells. The vaccines do this by triggering the human immune system to produce anti-spike antibodies that attach to the spike protein whenever they encounter it and neutralize the virus. All 17 versions of the virus tested so far have been neutralized, including the variant that is most common in the United States.

And, the new variant in the United Kingdom that is likely more easily spread person to person is also unlikely to evade the new vaccines, despite the presence of mutations in the spike glycoprotein. This is in part due to the fact that there are multiple sites on the spike protein that antibodies can target to neutralize the virus. This is being formally tested now.


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